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PubMed · 7229596

Wing buds with three ZPAs.

L E Iten·D J Murphy·L C Javois
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Abstract

It has been hypothesized that a diffusible morphogen emanates from the ZPA of the embryonic chick limb and that cells can have their presumptive fate respecified to form more posterior structures when exposed to a higher concentration of morphogen. Attempts to raise the concentration of morphogen by grafting two additional ZPAs into a host wing bud failed. Instead, the greater the positional disparity between the donor and host tissue at the graft sites, the greater the number of extra structures that formed.

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AnimalsChick EmbryoModels, BiologicalTransplantation, HomologousWings, AnimalJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.

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L E Iten, D J Murphy, L C Javois. 1981. Wing buds with three ZPAs.. https://doi.org/10.1002/jez.1402150113

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