Static input-output relations in the spinal recurrent inhibitory pathway.

S Cleveland; A Kuschmierz; H G Ross

doi:10.1007/bf00453372

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Static input-output relations in the spinal recurrent inhibitory pathway.

S Cleveland·A Kuschmierz·H G Ross

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Abstract

The static discharge rate of Renshaw cells (studied in deafferented, intercollicularly decerebrate cats) has a nonlinear dependence on the frequency of trains of stimulus impulses to alpha-motor axons in the ventral root. This dependence is well described by a rectangular hyperbola that approaches saturation with increasing stimulus frequency. The tendency to saturate is independent of the number of motor axons exciting a Renshaw cell. On average, the stimulus frequency at which the discharge rate reaches half its saturation value lies between 10 and 15 Hz. The effect of Renshaw cell activity -- measured as the antidromic inhibition of individual alpha-motoneurons -- reflects the forms of the static frequency characteristics. An electric circuit analog of the Renshaw cell membrane is presented which serves to explain the qualitative features of the static input-output relations; the nonlinearity is the result of synapses with linear properties acting together at the cell membrane.

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Animals Cats Electric Stimulation Electrophysiology Evoked Potentials Models, Neurological Motor Neurons Neural Inhibition Neural Pathways Spinal Nerve Roots Journal Article

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S Cleveland, A Kuschmierz, H G Ross. 1981. Static input-output relations in the spinal recurrent inhibitory pathway.. https://doi.org/10.1007/bf00453372

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