Mycoplasma capping on lymphocytes.

E J Stanbridge; R L Weiss

doi:10.1038/276583a0

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Mycoplasma capping on lymphocytes.

E J Stanbridge·R L Weiss

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Abstract

When mycoplasmas infect lymphocytes they behave as multivalent ligands and cap on the lymphoid cell surface in the absence of added specific antibody. There is an apparent high correlation between mycoplasma capping and blast transormation of the infected lymphocytes. Mycoplasma caps are shed from the surface of cells as an aggregate containing host membrane vesicles. This novel interaction may suggest a physiological role for the phenomenon of capping and may play a part in mycoplasma pathogenesis.

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Animals Binding Sites Cell Line Immunologic Capping Lipopolysaccharides Lymphocytes Mice Mycoplasma Spleen Journal Article Research Support, U.S. Gov't, P.H.S.

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E J Stanbridge, R L Weiss. 1978-12-07. Mycoplasma capping on lymphocytes.. https://doi.org/10.1038/276583a0

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