Exponential decrease during aging and random lifetime of mouse spermatogonial stem cells.

N Suzuki; H R Withers

doi:10.1126/science.725597

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PubMed · 725597

Exponential decrease during aging and random lifetime of mouse spermatogonial stem cells.

N Suzuki·H R Withers

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Abstract

Variation in the number of spermatogonial stem cells during the lifespan of the mouse was examined by assaying the number of clonogenic cells, that is, spermatogenic stem cells, surviving known doses of radiation. The results indicated that the stem cell number decreased exponentially with age.

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Aging Animals Dose-Response Relationship, Radiation Gamma Rays Male Mice Spermatogonia Spermatozoa Testis Journal Article Research Support, U.S. Gov't, P.H.S.

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N Suzuki, H R Withers. 1978-12-15. Exponential decrease during aging and random lifetime of mouse spermatogonial stem cells.. https://doi.org/10.1126/science.725597

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