Long lasting suppression of firing of cortical neurons and decrease in cortical blood flow following train pulse stimulation of the locus coeruleus in the cat.

Y Katayama; Y Ueno; T Tsukiyama; T Tsubokawa

doi:10.1016/0006-8993(81)91285-3

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Long lasting suppression of firing of cortical neurons and decrease in cortical blood flow following train pulse stimulation of the locus coeruleus in the cat.

Y Katayama·Y Ueno·T Tsukiyama·T Tsubokawa

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Abstract

Single neuron activity and local cerebral blood flow were recorded simultaneously in the same spot of the gyrus proreus in cats. Train pulse stimulation (10-20 Hz, 30 sec) of the ipsilateral locus coeruleus induced long lasting suppression of firing in up to 78% of neurons and decrease in local flow, which lasted 1.9-5.6 min and 3.8-6.5 min, respectively. Single pulse stimulation evoked inhibition of firing in 55% of the neurons investigated.

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Animals Cats Cerebral Cortex Cerebrovascular Circulation Evoked Potentials Locus Coeruleus Neural Inhibition Neurons Norepinephrine Journal Article Research Support, Non-U.S. Gov't

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Y Katayama, Y Ueno, T Tsukiyama, T Tsubokawa. 1981-07-06. Long lasting suppression of firing of cortical neurons and decrease in cortical blood flow following train pulse stimulation of the locus coeruleus in the cat.. https://doi.org/10.1016/0006-8993(81)91285-3

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