Developmental changes in brain template active region chromatin.

L Uphouse; B Tedeschi; H Brown

doi:10.1159/000112761

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Developmental changes in brain template active region chromatin.

L Uphouse·B Tedeschi·H Brown

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Abstract

The percentage of brain or liver chromatin in the template-active region was examined in rats of varying ages. Prenatally, there was an increase in the percentage of brain template-active region chromatin which declined near birth. After birth, the percentage of brain template-active region chromatin again increased to 3-6 days of age and then declined to adult levels at about 15 days of age. Liver exhibited a similar gestational change in the percentage of template-active region chromatin, but there was no recovery from the birth decline during postnatal development. These findings are discussed in terms of their contribution to the understanding of age-dependent changes in brain transcription.

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Aging Animals Brain Female Gestational Age Liver Male Nissl Bodies Pregnancy Rats Rats, Inbred F344 Templates, Genetic Transcription, Genetic Journal Article

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L Uphouse, B Tedeschi, H Brown. 1981. Developmental changes in brain template active region chromatin.. https://doi.org/10.1159/000112761

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