PubMed · 7290129
The source did not provide an abstract. Follow the original record for more information.
Explore connections, maps & timelines
P E Munday, A P Johnson, B J Thomas, D Taylor-Robinson. 1981-11-05. Chlamydia trachomatis proctitis.. https://doi.org/10.1056/nejm198111053051921
Cite the original work for its findings. Save a collection to share your selection of sources.
KEEP EXPLORING
An enzyme immunoassay (EIA) antigen detection system (MicroTrak, Syva), nucleic acid hybridization (PACE 2, Gen-Probe) and polymerase chain reaction (PCR) assay (Amplicor, Hoffmann-La Roche) were evaluated for the detection of Chlamydia trachomatis in a high-risk female population. Of 234 specimens, 42 (18%) were positive. The respective sensitivity of the EIA, RNA hybridization and the PCR was 81, 90 and 88%. When additionally performed on diluted specimens, PCR gave positive results for three of four PCR-negative specimens from EIA- and RNA-hybridization-positive women and a sensitivity of 95%. Thus, both techniques employing gene technology offered a clear improvement in sensitivity over the EIA. Future improvements in the PCR should be directed towards the elimination of polymerase inhibition.
The authors are analyzing their results of the treatment with roxithromycin 150 mg of the pelvic inflammatory disease, caused by chlamydia trachomatis. 29 patients with proved chlamydial infection were treated. The most popular diagnosis was cervicitis. 23 patients were totally cured, 4 patients were with considerable better status after the treatment, and 2 of the patients were with insignificant amelioration of the status. A conclusion can be made, that the roxithromycin is a very good alternative of the existing treatment with doxycicline.
Explore the source record for details and available documents.