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PubMed · 7300407

Ventricular function before and after mitral valve replacement.

M Kirschbaum·F Lumia·P Germon·V Maranhao·S D Cha·G Lemole
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Abstract

To evaluate right ventricular function following mitral valve replacement, we studied 84 patients with isolated mitral valve disease with the use of first-pass radionuclide angiography before, 1 week after, and up to 1 year after operation. The right ventricular ejection fraction for the entire group improved from 29% +/- 11% to 43% +/- 10% (p less than 0.001) at 1 week. This increase was maintained at 3 months (41% +/- 10%) and up to year after operation (40% +/- 12%). The improvement was found not to be influenced by either the type of valvular lesion or the presence and/or level of pulmonary hypertension. When the patients were grouped according to the type of prosthetic valve placed at operation, the right ventricular ejection fraction increased in all patients within 1 week of operation, with sustained improvement at 3 months postoperatively. Thereafter, it began to decline in patients receiving a Carpentier bioprosthesis while being maintained in those patients who received disc valves. Further analysis revealed that those patients who receiving the larger Carpentier bioprostheses had a greater deterioration of right ventricular function than those receiving the smaller Carpentier valves. Left ventricular function in the entire group was normal preoperatively (62% +/- 16%) and was unchanged at 1 week (60% +/- 16%) and a 1 year (59% +/- 16%) after operation.

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AdultAgedBioprosthesisCardiac OutputFemaleFollow-Up StudiesHeart Valve ProsthesisHumansMaleMiddle AgedMitral ValveMitral Valve InsufficiencyMitral Valve StenosisStroke VolumeJournal Article

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M Kirschbaum, F Lumia, P Germon, V Maranhao, S D Cha, G Lemole. 1981. Ventricular function before and after mitral valve replacement.. https://pubmed.ncbi.nlm.nih.gov/7300407/

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