Structure of the junction between communicating cells.

P N Unwin; G Zampighi

doi:10.1038/283545a0

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PubMed · 7354837

Structure of the junction between communicating cells.

P N Unwin·G Zampighi

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Abstract

An 18-A resolution map of the 'gap junction' has been obtained by electron microscopy. The protein oligomer in the junctional membranes, the 'connexon', is a cyclinder composed of six subunits which are titled around its axis. Analysis of two different subunit configurations suggests how the connexon might regulate the passage of small molecules between cell interiors.

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Animals Cell Communication Fourier Analysis Intercellular Junctions Liver Macromolecular Substances Membrane Proteins Molecular Weight Rats Journal Article Research Support, U.S. Gov't, P.H.S.

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P N Unwin, G Zampighi. 1980-02-07. Structure of the junction between communicating cells.. https://doi.org/10.1038/283545a0

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