Formation of apparent presynaptic elements in response to poly-basic compounds.

R W Burry

doi:10.1016/0006-8993(80)90588-0

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Formation of apparent presynaptic elements in response to poly-basic compounds.

R W Burry

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Abstract

Neuronal cell processes in dispersed cell culture grow out onto Sepharose beads coated with poly-basic proteins. Apparent presynaptic elements are formed by these neuronal processes with the bead serving as a postsynaptic element. It is suggested that electrostatic binding between poly-acidic groups on the presynaptic element and poly-basic troups on the postsynaptic element is one of the initial steps in the formation of a synaptic contact in culture.

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Animals Cell Adhesion Cell Aggregation Cell Communication Cells, Cultured Cerebellum Hydrogen-Ion Concentration Neurons Proteins Rats Synapses Journal Article Research Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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R W Burry. 1980-02-17. Formation of apparent presynaptic elements in response to poly-basic compounds.. https://doi.org/10.1016/0006-8993(80)90588-0

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