Mucus-stimulating factor in tears.

R M Franklin; B G Bang

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PubMed · 7358498

Mucus-stimulating factor in tears.

R M Franklin·B G Bang

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Abstract

Mechanisms responsible for regulation of tear film mucus are poorly understood. Humoral factors responsible for stimulation of mucus secretion can be studied in vitro by using the free-swimming urn cell, a normal component of the coelomic fluid of the marine invertebrate Sipunculus nudus. With this system, a tear mucus-stimulating factor was found in normal human tears but was markedly decreased in patients with dry eye syndromes. It is suggested that a mucus-stimulating factor exists in normal human tears and that a decrease in this substance may be instrumental in the pathophysiology of certain dry eye syndromes.

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Animals Biological Assay Cells Humans In Vitro Techniques Keratoconjunctivitis Macromolecular Substances Mucus Nematoda Tears Xerophthalmia Journal Article Research Support, U.S. Gov't, P.H.S.

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R M Franklin, B G Bang. 1980. Mucus-stimulating factor in tears.. https://pubmed.ncbi.nlm.nih.gov/7358498/

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