Fatty acids bound to serumalbumin decrease the half-life of thromboxane A2.

M Lagarde; B Velardo; M Blanc; M Dechavanne

doi:10.1016/s0090-6980(80)80046-3

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Fatty acids bound to serumalbumin decrease the half-life of thromboxane A2.

M Lagarde·B Velardo·M Blanc·M Dechavanne

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Abstract

The half-life of thromboxane A2 is increased in plasma as well as in a buffer containing serumalbumin. Moreover, the half-life of thromboxane A2 depends on the amount of unesterified fatty acids bound to albumin. When more fatty acids are bound, the half-life is shortened. This shortening is accompanied by a decrease of the aggregating activity of thromboxane A2.

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Chemical Phenomena Chemistry Fatty Acids, Nonesterified Half-Life Humans Platelet Aggregation Protein Binding Serum Albumin Thromboxane A2 Thromboxanes Journal Article

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M Lagarde, B Velardo, M Blanc, M Dechavanne. 1980. Fatty acids bound to serumalbumin decrease the half-life of thromboxane A2.. https://doi.org/10.1016/s0090-6980(80)80046-3

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