Titanium retention in mice.

R G Thomas; R F Archuleta

doi:10.1016/0378-4274(80)90177-0

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Titanium retention in mice.

R G Thomas·R F Archuleta

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Abstract

Intraperitoneal (i.p.) and intravenous (i.v.) injection of 44Ti in a chloride solution into mice produced no detectable translocation in body fluids. There was no obvious interorgan exchange up to 16 days after injection. The whole body biological retention half-lives had a mean of 642 days for both routes, another indication of 44Ti's insolubility in body fluids. Absorption from the gastrointestinal (g.i.) tract after administration by stomach tube was negligible. The threshold limit value (TLV) for titanium in air, based upon nuisance dust, is acceptable based upon the results of this study.

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Animals Female Half-Life Injections, Intraperitoneal Injections, Intravenous Intestinal Absorption Male Mice Time Factors Tissue Distribution Titanium Journal Article

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R G Thomas, R F Archuleta. 1980. Titanium retention in mice.. https://doi.org/10.1016/0378-4274(80)90177-0

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