[Hydrocortisone-receptor complex binding with various nonhistone protein groups].

E S Gevorkian

PubMed · 7423883

[Hydrocortisone-receptor complex binding with various nonhistone protein groups].

Abstract

Complexes containing DNA and various groups of non-histone proteins were isolated from rat liver cells. Deproteinized DNA was bound with the hydrocortisone-receptor complex at the highest rate in vitro. Non-histone proteins from the chromatin fraction did not bind with the hormone-receptor complex. Unsaturability of DNA in reaction with the complex appears to indicate the low specificity of binding.

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Animals Chromatin Chromosomal Proteins, Non-Histone Cytosol DNA Female Hydrocortisone In Vitro Techniques Liver Male Protein Binding Rats Receptors, Glucocorticoid Receptors, Steroid English Abstract Journal Article

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E S Gevorkian. [Hydrocortisone-receptor complex binding with various nonhistone protein groups].. https://pubmed.ncbi.nlm.nih.gov/7423883/

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