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PubMed · 7445916

Estrogenic absorption through the skin: an experimental study.

C Goisis·F Goisis·R Tammiso
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Abstract

Our results show in an unquestionable way that both the steroid (ethinylestradiol) and non-steroid (Ralone) estrogens studied by us were absorbed percutaneously by the rat. They also demonstrate that both estrogens affected target organs in a quite similar way being proportionally dependent upon the 1-to-1,000 ratio existing between them, as established on the basis of a known activity parameter. When one of the two estrogens is given for therapeutical purposes its systemic effects are of a dose-related type.

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AnimalsBody WeightCastrationEndometriumEthinyl EstradiolFemaleGenitalia, FemaleOrgan SizeRatsResorcinolsSkin AbsorptionTissue DistributionVaginaZeranolJournal Article

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C Goisis, F Goisis, R Tammiso. 1980. Estrogenic absorption through the skin: an experimental study.. https://pubmed.ncbi.nlm.nih.gov/7445916/

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