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Decrease in human plasma prolactin levels by oral prostaglandin E2 in early puerperium.

F Caminiti·M De Murtas·G Parodo·U Lecca·A Nasi
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Abstract

Eight milligrams of prostaglandin E2 (PGE2; 2 mg every 30 min) were given orally to 12 puerperal women on day 4 after delivery. Plasma levels of prolactin showed a significant decrease in comparison with basal levels and with those of controls sampled over a similar period. The same dose of PGE2 was ineffective in modifying the plasma prolactin levels in four puerperal women on day 30 after delivery and in four non-pregnant women with normal levels of prolactin. It is suggested that a PGE2-induced decrease in prolactin could be mediated by hypothalamic dopaminergic neurones.

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FemaleHumansPostpartum PeriodPregnancyProlactinProstaglandins EJournal Article

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F Caminiti, M De Murtas, G Parodo, U Lecca, A Nasi. 1980. Decrease in human plasma prolactin levels by oral prostaglandin E2 in early puerperium.. https://doi.org/10.1677/joe.0.0870333

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