Interactions between reserpine and anticonvulsants on convulsion parameters.

K S Iyer; R V Thampuran

PubMed · 750490

Interactions between reserpine and anticonvulsants on convulsion parameters.

Abstract

Reserpine lowered the MET and this lowering of MET was antagonized by chloridaze-poxide but not by acetazoleamide and phenytoin. With increasing doses of reserpine the extension time in an MES test was increased and this was antagonized by all anticonvulsants tested namely acetazolamide, chlordiazepoxide, phenytoin and propranolol. High doses of reserpine abolished flexion component and this was restored by propranolol, phenytoin, atropine, chlordiazepoxide and acetazolamide.

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Animals Anticonvulsants Drug Interactions Electroshock Hindlimb Male Rats Reflex Reserpine Seizures Journal Article

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K S Iyer, R V Thampuran. Interactions between reserpine and anticonvulsants on convulsion parameters.. https://pubmed.ncbi.nlm.nih.gov/750490/

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