Mechanically sensitive, nonselective cation channels.

X C Yang; F Sachs

doi:10.1007/978-3-0348-7327-7_5

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Mechanically sensitive, nonselective cation channels.

X C Yang·F Sachs

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Abstract

Mechanically sensitive channels (MSCs) are ubiquitous in plant and animal cells. They respond primarily to membrane tension, thus making them good transducers for forces derived from osmotic or hydraulic gradients and shear stress. They may also be modulated by membrane voltage and various ligands. MSCs are most commonly cation selective, passing calcium as well as monovalent ions, but some are K+ selective, and a few are anion selective. MSCs occur at a density of about 0.2-5 per microns2. The universal distribution and biophysical properties of MSCs make them the ideal mechanotransducers in a wide variety of cellular processes.

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Animals Cations Cytoskeleton Drosophila Ion Channel Gating Ion Channels Kinetics Models, Biological Plant Physiological Phenomena Potassium Channels Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.Review

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X C Yang, F Sachs. 1993. Mechanically sensitive, nonselective cation channels.. https://doi.org/10.1007/978-3-0348-7327-7_5

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