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CD11/CD18 panel report for swine CD workshop.

Y B Kim·J Zhang·W C Davis·J K Lunney
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Abstract

Five monoclonal antibodies (mAbs), PNK-I (W #037), H20A (W #077), MUC76A (W #078), MUC93A (W #079) and MHM23 (W #136) of CD11/18 panels reacted with 80-96% of porcine PBMC and PMN. Epitope mapping studies by competitive binding of mAb by flow cytometric analysis based on PNK-I as CD18 epitope defining antibody resulted H20A and MHM23 mAbs bind to the same shared epitope as PNK-I, but MUC76A and MUC93A mAbs were distinct from PNK-I. Thus, PNK-I, H20A and MHM23 were designated as CD18a mAbs.

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AnimalsAntibodies, MonoclonalBinding, CompetitiveCD11 AntigensCD18 AntigensEpitopesFlow CytometryLeukocytes, MononuclearNeutrophilsSwineJournal Article

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Y B Kim, J Zhang, W C Davis, J K Lunney. 1994. CD11/CD18 panel report for swine CD workshop.. https://doi.org/10.1016/0165-2427(94)90150-3

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