New methods to predict MHC-binding sequences within protein antigens.

J Hammer

doi:10.1016/0952-7915(95)80013-1

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New methods to predict MHC-binding sequences within protein antigens.

J Hammer

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Abstract

The identification and analysis of MHC-binding sequences within protein antigens, and ultimately the ability to predict them, is central to immunology. Recent advances have revealed increasingly complex MHC-binding motifs and allows prediction of sequences that bind to both classes of MHC molecules. The systematic characterization of binding motifs for all human MHC alleles is now possible and will facilitate the design of peptides for therapeutic intervention.

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Amino Acid Sequence Animals Epitopes Humans Immunologic Techniques Major Histocompatibility Complex Molecular Sequence Data Protein Binding Proteins Journal Article Review

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J Hammer. 1995. New methods to predict MHC-binding sequences within protein antigens.. https://doi.org/10.1016/0952-7915(95)80013-1

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