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PubMed · 7546402

Mouse NK1+ T cells.

A Bendelac
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Abstract

Mouse NK1+ T cells constitute a special subset of alpha beta TCR+ T cells that express natural killer surface receptors and are thought to play an immunoregulatory role because of their unique ability to secrete IL-4 within minutes of primary activation. The recent discovery that they recognize non-polymorphic MHC class I like ligands encoded by CD1 family genes sheds a new light on unusual aspects of their development as well as on some of the possible ways in which they might influence the regulation of the T-helper cell (types 1 and 2) classes of immune responses.

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Amino Acid SequenceAnimalsAntigens, CD1Base SequenceCD4-Positive T-LymphocytesEpitopesHistocompatibility Antigens Class IKiller Cells, NaturalLymphocyte ActivationMiceMice, Inbred StrainsMice, KnockoutMice, NudeMice, TransgenicModels, ImmunologicalMolecular Sequence DataPhenotypeReceptors, Antigen, T-Cell, alpha-betaSpleenT-Lymphocyte SubsetsThymus GlandJournal ArticleReview

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A Bendelac. 1995. Mouse NK1+ T cells.. https://doi.org/10.1016/0952-7915(95)80112-x

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Amino Acid Sequence↗