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PubMed · 7548713

Dose-response models with covariates.

M C Wijesinha·S Piantadosi
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Abstract

Two approaches are presented to incorporate covariate effects into dose-response models. The first approach postulates a parametric form for the dose-response function with the resulting parameters then assumed to depend on the covariates. The second approach is semi-parametric: it assumes that the logit ratio (the difference between the logit of success rate at the covariate level and that of the baseline level) can be expressed as a regression model in the covariate effects and the dose level. We present results of a simulation study which compares the efficiency of the two approaches.

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Analysis of VarianceAnimalsDose-Response Relationship, DrugHumansMathematicsModels, StatisticalProbabilityRegression AnalysisSoftwareComparative StudyJournal Article

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M C Wijesinha, S Piantadosi. 1995. Dose-response models with covariates.. https://pubmed.ncbi.nlm.nih.gov/7548713/

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