A molecular basis for T-dependent B cell activation.

P Lane

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PubMed · 7575354

A molecular basis for T-dependent B cell activation.

P Lane

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Abstract

This review has concentrated on the key molecules which regulate T-dependent B cell activation in the context of the structural architecture within secondary lymphoid tissue where B cell immune responses occur. CD40L clearly plays a key role in driving B cells to proliferate within germinal centers, and although the data is conflicting, there is some evidence that the induction of CD40L is dependent on costimulation through CD28.

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Animals B-Lymphocytes CD28 Antigens CD40 Antigens Cell Communication Humans Lymphocyte Activation Lymphoid Tissue Lymphokines T-Lymphocytes Journal Article Research Support, Non-U.S. Gov't Review

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P Lane. 1995. A molecular basis for T-dependent B cell activation.. https://pubmed.ncbi.nlm.nih.gov/7575354/

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