Progress in AIDS vaccine development.

M I Johnston

doi:10.1159/000237173

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Progress in AIDS vaccine development.

M I Johnston

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Abstract

Because of a unique combination of challenges facing human immunodeficiency virus vaccine developers, a number of traditional and novel vaccine designs are being evaluated essentially in parallel. Monomeric proteins, poxvirus vectors, peptides, and particle-based candidate vaccines have entered or will soon enter human trials. Other designs are at earlier stages of development. All candidates evaluated to date in phase I/II human trials have proven safe and immunogenic. One or more of the most promising designs will soon progress to 'test of concept' clinical trials to determine efficacy.

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AIDS Vaccines Acquired Immunodeficiency Syndrome Animals Clinical Trials, Phase I as Topic Clinical Trials, Phase II as Topic Drug Design Gene Products, env Gene Products, gag HIV Antigens HIV Infections Humans Poxviridae Vaccines, Synthetic Journal Article Review

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M I Johnston. 1995. Progress in AIDS vaccine development.. https://doi.org/10.1159/000237173

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