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PubMed · 759039

Folic acid dependent hypersarcosinaemia.

W Blom·J Fernandes
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Abstract

Hypersarcosinaemia is a rare inborn error of metabolism, caused by a deficiency of the sarcosine dehydrogenase complex with tetrahydrofolate as a formaldehyde acceptor needed for the sarcosine-glycine conversion. Prolonged therapy with folic acid on a hypersarcosinaemic patient resulted in a significant effect on the urinary excretion of sarcosine, leading to the conclusion that the patient has a folic acid dependent hypersarcosinaemia.

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Amino Acid Metabolism, Inborn ErrorsChildFemaleFolic AcidHistidineHumansOxidoreductasesSarcosineVitamin B 12Case ReportsJournal Article

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BibTeXRIS

W Blom, J Fernandes. 1979-01-15. Folic acid dependent hypersarcosinaemia.. https://doi.org/10.1016/0009-8981(79)90445-5

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