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PubMed · 7593003

Hydroxyapatite-clay bone fixation for loaded implants.

M Maruyama
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Abstract

A clay containing hydroxyapatite (HA clay), which was made by mixing HA granules (range of sizes: 0.1-0.3 mm) and a saline solution of sodium alginate, was inserted into the medullary canal of an osteotomized rabbit's tibia with a Ti-6Al-4V titanium alloy implant. Each implant had a conical portion for bearing load. The shear strength of the bone-implant interface for the implant with HA clay was significantly greater than that for the implant without HA clay 3 months postoperatively (P < .02), while there was no significant difference between the two strengths 1 week postoperatively. Under microscopic observation, the percentage of area of newly developed bone was also significantly greater for the implant with HA clay than for the implant without HA clay 3 months postoperatively (P < .04). This study suggests that HA clay encouraged adequate bone fixation of the loaded implant in 3 months, while the clay was not effective for immediate fixation.

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AlloysAnimalsBone DevelopmentBone and BonesHydroxyapatitesOrthopedic Fixation DevicesProstheses and ImplantsRabbitsTibiaTitaniumJournal Article

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M Maruyama. 1995. Hydroxyapatite-clay bone fixation for loaded implants.. https://doi.org/10.1002/jbm.820290602

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