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Integrin expression in head and neck cancers.

G Cortesina·M Sacchi·M Bussi·B Panizzut·S Ferro·M T Carlevato·P C Marchisio
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Abstract

Neoplastic transformation results in rearrangement of the cell membrane with a breakdown of the regular expression of adhesion molecules such as integrins. A relationship may exist between the intensity of this alteration, and the form it takes, and a tumour's ability to metastatise. We studied this possibility by investigating the epithelial integrin expression of 35 head and neck squamous cell carcinomas. Two types of positivity were observed: one associated with tumours with a better prognostic index, the other with those characterized by greater malignancy.

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Carcinoma, Squamous CellCell Adhesion MoleculesCulture TechniquesEpitheliumHumansIntegrinsLamininLaryngeal NeoplasmsLarynxNeoplasm StagingOropharyngeal NeoplasmsOropharynxPrognosisReceptors, LamininKalininJournal ArticleResearch Support, Non-U.S. Gov't

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G Cortesina, M Sacchi, M Bussi, B Panizzut, S Ferro, M T Carlevato, P C Marchisio. 1995. Integrin expression in head and neck cancers.. https://doi.org/10.3109/00016489509139322

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