Transcription factors: structure, function, and implication in malignant growth.

A G Papavassiliou

PubMed · 7645977

Transcription factors: structure, function, and implication in malignant growth.

Abstract

Transcription factors are the principal modulators of gene expression patterns in the organism and are thus involved in processes leading to changes in developmental programmes, responses to growth and differentiation signals, and some of the alterations causing neoplastic transformation. The present overview deals with general aspects of the structure, function, and regulation of transcription factors, in relation to their physiological role and oncogenic potential.

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Amino Acid Sequence Cell Differentiation Cell Division DNA-Binding Proteins Gene Expression Gene Expression Regulation, Neoplastic Humans Neoplasms Protein Structure, Secondary Reference Values Transcription Factors Zinc Fingers Journal Article Review

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A G Papavassiliou. Transcription factors: structure, function, and implication in malignant growth.. https://pubmed.ncbi.nlm.nih.gov/7645977/

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