[Cyclins and carcinogenesis].

C Bréchot

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PubMed · 7648370

[Cyclins and carcinogenesis].

C Bréchot

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Abstract

Cell cycle progression is regulated by the sequential activation of cyclins expression and their association to the cyclin dependent kinases (CDK). Several in vitro and in vivo studies indicate that inappropriate cyclin expression (cyclins D, E, A) in the cell, whether or not due to chromosomal rearrangements, can participate in cell transformation. Thus these studies implicate cyclins in human carcinogenesis.

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Animals Biomarkers, Tumor Cell Cycle Cyclic AMP Cyclins G1 Phase Humans In Vitro Techniques Neoplasms Neoplasms, Experimental S Phase Transcription, Genetic Transduction, Genetic English Abstract Journal Article

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C Bréchot. 1995. [Cyclins and carcinogenesis].. https://pubmed.ncbi.nlm.nih.gov/7648370/

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