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The need for ventilatory support during bystander CPR.

R A Berg·D Wilcoxson·R W Hilwig·K B Kern·A B Sanders·C W Otto·D K Eklund·G A Ewy
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Abstract

STUDY OBJECTIVE: To compare CPR with chest compressions plus ventilatory support (CC+V) and chest compressions alone (CC). DESIGN: Prospective, randomized study. SETTING: Research laboratory. INTERVENTIONS: After 2 minutes of ventricular fibrillation, 18 domestic swine (20 to 35 kg) were treated first with CC or CC+V for 10 minutes, then with standard advanced cardiac life support. RESULTS: Hemodynamics, survival, and neurologic outcome were determined. All 8 swine subjected to CC+V and all 10 subjected to CC showed return of spontaneous circulation. One animal in each group died within 1 hour. Seven of 8 animals in the CC+V group survived for 24 and 48 hours, compared with 9 of 10 CC animals at 24 hours and 8 of 10 at 48 hours. All 48-hour survivors were neurologically normal. CONCLUSION: In this experimental model of bystander CPR, we could not detect a difference in hemodynamics, 48-hour survival, or neurologic outcome when CPR was applied with and without ventilatory support.

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AnimalsCardiopulmonary ResuscitationDisease Models, AnimalEmergency Medical ServicesHeart MassageHemodynamicsOxygenRandom AllocationSurvival AnalysisSwineTime FactorsTreatment OutcomeVentricular FibrillationComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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R A Berg, D Wilcoxson, R W Hilwig, K B Kern, A B Sanders, C W Otto, D K Eklund, G A Ewy. 1995. The need for ventilatory support during bystander CPR.. https://doi.org/10.1016/s0196-0644(95)70084-6

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