Cyclin E is expressed in neurons and forms complexes with cdk5.

M Miyajima; H O Nornes; T Neuman

doi:10.1097/00001756-199505300-00014

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Cyclin E is expressed in neurons and forms complexes with cdk5.

M Miyajima·H O Nornes·T Neuman

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Abstract

Expression of cyclin dependent kinase cdk5 and its regulator p35 has been shown in the cytoplasm of adult neurons. Here we demonstrate that another potential regulator of cdk5, cyclin E, is expressed in the nervous system and forms complexes with cdk5. Western blot analyses identifies expression of two forms of cyclin E in the mouse nervous system with the 56 kDa form mainly expressed in neurons and 51 kDa form expressed in astrocytes and oligodendrocytes.

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Animals Blotting, Northern Blotting, Western Cells, Cultured Cerebral Cortex Cyclin-Dependent Kinase 5 Cyclin-Dependent Kinases Cyclins Gene Expression Mice Neurons Protein Serine-Threonine Kinases Spinal Cord Journal Article Research Support, Non-U.S. Gov't

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M Miyajima, H O Nornes, T Neuman. 1995-05-30. Cyclin E is expressed in neurons and forms complexes with cdk5.. https://doi.org/10.1097/00001756-199505300-00014

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