PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 7686727

Differential diagnosis between learning-disabled and dysphasic children.

J Fortin·J G Dudley·Y Joanette
View original source ↗Export metadata ↓

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

ApraxiasAuditory PerceptionChildChild DevelopmentChild LanguageDevelopmental DisabilitiesDiagnosis, DifferentialFemaleHumansLanguage DisordersLanguage TestsLearning DisabilitiesMaleSpeech Discrimination TestsSpeech DisordersJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J Fortin, J G Dudley, Y Joanette. 1993-06-14. Differential diagnosis between learning-disabled and dysphasic children.. https://doi.org/10.1111/j.1749-6632.1993.tb22990.x

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Novel splicing mutation in the progranulin gene causing familial corticobasal syndrome.

Corticobasal syndrome (CBS) is a rare cognitive and movement disorder characterized by asymmetric rigidity, apraxia, alien-limb phenomenon, cortical sensory loss, myoclonus, focal dystonia, and dementia. It occurs along the clinical spectrum of frontotemporal lobar degeneration (FTLD), which has recently been shown to segregate with truncating mutations in progranulin (PGRN), a multifunctional growth factor thought to promote neuronal survival. This study identifies a novel splice donor site mutation in the PGRN gene (IVS7+1G-->A) that segregates with CBS in a Canadian family of Chinese origin. We confirmed the absence of the mutant PGRN allele in the RT-PCR product which supports the model of haploinsufficiency for PGRN-linked disease. This report of mutation in the PGRN gene in CBS extends the evidence for genetic and phenotypic heterogeneity in FTLD spectrum disorders.

Apraxias↗