Vitronectin and its receptors.

B Felding-Habermann; D A Cheresh

doi:10.1016/0955-0674(93)90036-p

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Vitronectin and its receptors.

B Felding-Habermann·D A Cheresh

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Abstract

The extracellular matrix protein vitronectin is recognized as an adhesive substrate by cells expressing at least one of four known vitronectin receptors: integrins alpha v beta 1, alpha v beta 3, alpha v beta 5 or alpha IIb beta 3. Cell interaction with vitronectin may induce spreading and migration and have an effect on cell growth and differentiation in specific processes, such as tumor growth and metastasis, wound healing, bone resorption and viral infection.

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Animals Apoptosis Bone Resorption Cell Adhesion Cell Differentiation Cell Division Cell Movement Extracellular Matrix Proteins Glycoproteins Humans Integrins Neoplasm Metastasis Neoplasms Receptors, Cytoadhesin Receptors, Vitronectin Signal Transduction Vitronectin Journal Article Review

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B Felding-Habermann, D A Cheresh. 1993. Vitronectin and its receptors.. https://doi.org/10.1016/0955-0674(93)90036-p

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