PubMed · 7736001
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H Itoh, K Hirata. 1994. [Pseudomembranous enterocolitis].. https://pubmed.ncbi.nlm.nih.gov/7736001/
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Meckel's diverticulum occurs in approximately 2% of the general population and is usually asymptomatic. Four percent of cases will present as an acute abdomen caused by intestinal obstruction, gastrointestinal bleeding, and inflammation. A neonatal presentation of Meckel's diverticulum mimicking necrotizing enterocolitis is described.
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Blood levels of gastrin, neurotensin and vasoactive peptide (VIP) were estimated in 14 premature infants with necrotizing enterocolitis (NEC) and in 12 controls. In comparison to the control group, infants with NEC had (a) significantly lower gastrin levels both before [9.3 (7.8) versus 33.7 (27.1)] and after [52.4 (48.1) versus 100.8 (50.9)] the development of NEC; (b) significantly lower neurotensin levels only after the development of NEC [37.8 (10.4) versus 54.5 (20.6)1; and (c) no significant difference in VIP values [25.4 (9.7) versus 18.9 (9.9) and 24.5 (15.7) versus 26.1 (19.1)]. It is concluded that NEC can adversely affect gastrin and neurotensin concentrations in the blood.