PubMed · 7746535
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M Gritter. 1995. Latex hypersensitivity.. https://doi.org/10.1097/00152193-199505000-00015
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A case of opioid withdrawal precipitated in an opioid-dependent person by low plasma levels of naloxone is presented. In this patient, changes were observed in the hypothalamic-pituitary-adrenal (HPA) axis that preceded the clinical symptoms and adrenergic signs of withdrawal. Plasma naloxone levels were strongly correlated with plasma cortisol levels (P < .0001, R2 = .73, r = .85). In addition, these neuroendocrine changes persisted after adrenergic changes and clinical symptoms had been ameliorated by administration of a short-acting opioid agonist. It is suggested that the HPA axis is a more sensitive indicator of opioid withdrawal than the adrenergic system.
It is often assumed that homeopathy, even though possibly ineffective, is free of risks. This notion is questioned in this review. Side-effects and complications associated with homeopathy have been reported in the literature. Furthermore the question whether the homeopath is risk-free in all cases needs discussing. As a case in point attitude of some homeopaths towards immunization is quoted as an example of particular concern. On the basis of these data the notion of totally risk-free homeopathy is untenable.