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The joint, a redox sensitive microenvironment?--an hypothesis.

T Sahinoglu·C R Stevens·D R Blake
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Abstract

Antioxidant depletion in a normal adult increases the risk of developing rheumatoid arthritis (1). We discuss how redox processes "control" the inflammatory reaction and suggest that the synovium is a peculiarly "redox-sensitive" microenvironment. This discussion will be illustrated by a zonal model of tissue injury to represent the diseased synovium.

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AnimalsArthritisHumansJointsModels, BiologicalOxidation-ReductionSynovial MembraneJournal ArticleResearch Support, Non-U.S. Gov'tReview

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T Sahinoglu, C R Stevens, D R Blake. 1995. The joint, a redox sensitive microenvironment?--an hypothesis.. https://doi.org/10.3109/03009749509100915

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