A new material with theoretical osteoinductive properties: experimental evaluation.

R Giardino; R Mongiorgi; G Bertocchi; M Fini; G Giavaresi; S Capelli

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PubMed · 7748531

A new material with theoretical osteoinductive properties: experimental evaluation.

R Giardino·R Mongiorgi·G Bertocchi·M Fini·G Giavaresi·S Capelli

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Abstract

An intensive research for bone substitutes has been in progress for several decades in order to find a new ideal material for bone replacement. In the present study the Authors report some data on a new developed material in comparison with synthetic hydroxyapatite. The new material was characterised by means of a crystallographic spectroscopic and chemical study. An in vitro test was also performed using murine fibroblasts. The results of this preliminary study showed that the sintered material has an and beta-tricalcium-phosphate (TCP) lattice depending on thermal treatment in accordance with literature data. Moreover, it showed a high level of biocompatibility. Though it is still in an investigation stage, perhaps this biomaterial is a highly reactive and unstable compound that could interact with CO2 and H2O.

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Animals Biocompatible Materials Bone Remodeling Calcium Phosphates Cell Line Crystallography, X-Ray Durapatite Fibroblasts Hot Temperature L-Lactate Dehydrogenase Mice Spectrophotometry, Infrared Comparative Study Journal Article Research Support, Non-U.S. Gov't

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R Giardino, R Mongiorgi, G Bertocchi, M Fini, G Giavaresi, S Capelli. 1994. A new material with theoretical osteoinductive properties: experimental evaluation.. https://pubmed.ncbi.nlm.nih.gov/7748531/

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