[Adipose tissue. Hidden aspects].

G Ailhaud

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PubMed · 7755345

[Adipose tissue. Hidden aspects].

G Ailhaud

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Abstract

Adipose differentiation is a sequential process (adipoblasts-->preadipocytes-->adipocytes). Adipogenic factors are only involved in the terminal differentiation of preadipocytes to adipocytes by means of circulating hormones (growth hormone, glucocorticoids, insulin, triiodothyronine) and locally produced hormones (prostacyclin, IGF-I). Fatty acids also behave as hormones and act as transcriptional regulators of lipid-related genes. Once differentiated, adipocytes become secretory cells able to synthetize and release numerous peptide and nonpeptide compounds, suggesting a potential link between excess of adipose tissue mass and various physiopathologic consequences.

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G Ailhaud. 1995. [Adipose tissue. Hidden aspects].. https://pubmed.ncbi.nlm.nih.gov/7755345/

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