Recent advances in phage display.

C F Barbas

doi:10.1016/0958-1669(93)90072-5

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PubMed · 7764201

Recent advances in phage display.

C F Barbas

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Abstract

The selection of peptides and proteins from libraries expressed on the surface of filamentous phage is becoming an important tool in biotechnology. Recent developments have shown that peptides can be selected to bind receptors and antibodies, while semisynthetic antibodies can be selected to bind almost any target. Phage display has allowed the routine isolation of therapeutically interesting human antibodies. Phage are also being utilized to examine the specificities of natural enzymes as well as to evolve novel enzymes de novo.

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Amino Acid Sequence Animals Antibodies Bacteriophages Biotechnology Gene Library Humans Molecular Sequence Data Peptides Protein Engineering Recombinant Proteins Journal Article Review

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C F Barbas. 1993. Recent advances in phage display.. https://doi.org/10.1016/0958-1669(93)90072-5

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