Remotely related sequences and structures: analysis and predictive modelling.

W R Taylor

doi:10.1016/0167-7799(94)90075-2

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Remotely related sequences and structures: analysis and predictive modelling.

W R Taylor

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Abstract

Through the comprehensive analysis of protein sequence and structural data, relationships can be established that suggest, with varying degrees of success, structural models for a protein for which only the sequence is known. The certainty with which a model can be proposed depends on the degree of similarity between the sequence of unknown structure and the sequence of a protein of known structure. Methods are being developed to detect remote similarities between sequences or structures, and to predict protein structure based on such small levels of similarity.

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Amino Acid Sequence Animals Humans Models, Molecular Molecular Sequence Data Protein Conformation Sequence Homology, Amino Acid Journal Article Review

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W R Taylor. 1994. Remotely related sequences and structures: analysis and predictive modelling.. https://doi.org/10.1016/0167-7799(94)90075-2

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