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The SWI-SNF complex: a chromatin remodeling machine?

C L Peterson·J W Tamkun
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Abstract

The SWI-SNF complex plays a key role in the regulation of eukaryotic gene expression. Genetic studies in the yeast Saccharomyces cerevisiae suggest that one role for the complex is to antagonize chromatin-mediated repression of transcription. Recent biochemical studies indicate that S. cerevisiae and putative human SWI-SNF complexes use the energy of ATP hydrolysis to disrupt nucleosome structure.

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AnimalsChromatinDNA-Binding ProteinsFungal ProteinsHumansSaccharomyces cerevisiaeTranscription FactorsJournal ArticleReview

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C L Peterson, J W Tamkun. 1995. The SWI-SNF complex: a chromatin remodeling machine?. https://doi.org/10.1016/s0968-0004(00)88990-2

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