Turing structures in a system with regulated gap-junctions.

C T Klein; F F Seelig

doi:10.1016/0303-2647(94)01478-p

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Turing structures in a system with regulated gap-junctions.

C T Klein·F F Seelig

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Abstract

In two coupled cells, each containing a bisubstrate-kinetics reaction system, the two substrates can cross the membranes through gap-junction protein channels (gating). Passing through the gap-junctions is controlled by one of the substrates, thus resulting in non-linear diffusion. Linear stability analysis gives the conditions, under which the symmetric fixpoint becomes unstable, leading to spatial asymmetry (Turing structures). The implications for morphogenesis are discussed.

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Animals Biological Transport, Active Cell Compartmentation Diffusion Enzymes Gap Junctions Ion Channel Gating Kinetics Models, Biological Journal Article

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C T Klein, F F Seelig. 1995. Turing structures in a system with regulated gap-junctions.. https://doi.org/10.1016/0303-2647(94)01478-p

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