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Suppressor T cells and suppressor factor.

B Benacerraf
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Abstract

The ability to suppress antibody response to specific antigens has been found to be inherent in a subpopulation of T lymphocytes. The suppressor pathway has been shown to involve an initial T-cell clone that that elaborates a soluble factor which, in turn, induces a second cohort of effector cells. The implications of this system for autoimmune and neoplastic diseases--and some relevant experiments--are discussed.

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AnimalsAntibody FormationCarrier ProteinsCyclophosphamideEpitopesHistocompatibility AntigensImmune SeraImmune ToleranceKiller Cells, NaturalLymphocyte CooperationMiceMice, Inbred StrainsNeoplasmsSuppression, GeneticT-LymphocytesJournal Article

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B Benacerraf. 1978. Suppressor T cells and suppressor factor.. https://doi.org/10.1080/21548331.1978.11707315

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