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PubMed · 7784827

Hypersensitivity hepatitis due to pyrazinamide.

X Corbella·M Vadillo·C Cabellos·P Fernandez-Viladrich·G Rufi
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Abstract

Pyrazinamide hepatotoxicity is considered secondary to a direct and dose-related toxic effect. At currently used doses, pyrazinamide provides effective short-term treatment and is free from serious side effects. We report a case of pyrazinamide-induced hepatitis for which the rechallenge data strongly suggest a hypersensitivity mechanism.

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Acute DiseaseChemical and Drug Induced Liver InjuryDose-Response Relationship, DrugDrug HypersensitivityFemaleHumansMiddle AgedPyrazinamideCase ReportsJournal Article

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X Corbella, M Vadillo, C Cabellos, P Fernandez-Viladrich, G Rufi. 1995. Hypersensitivity hepatitis due to pyrazinamide.. https://doi.org/10.3109/00365549509018984

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