Vascular mineralization in the monkey brain.

T Yanai; T Masegi; K Ueda; J Manabe; M Teranishi; M Takaoka; N Matsunuma; K Fukuda; N Goto; K Fujiwara

doi:10.1177/030098589403100506

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PubMed · 7801432

Vascular mineralization in the monkey brain.

T Yanai·T Masegi·K Ueda·J Manabe·M Teranishi·M Takaoka·N Matsunuma·K Fukuda·N Goto·K Fujiwara

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Abstract

Mineralization of various degrees was found in the brains of 79 (59%) of 134 cynomolgus monkeys (Macaca fascicularis). There was no age dependency in the incidence or severity, nor were there any abnormalities in growth, weight gain, or neurologic signs, although a slight sex difference was observed. The lesions, which were basophilic and intensely positive for periodic acid-Schiff or von Kossa stain, occurred in the vascular walls of the globus pallidus in two types: globoid bodies with prominent concentric lamellar structures in and around the arteriolar and venular wall (type A) and fine granules in the media of small or medium-sized arteries (type B). Electron microscopic examination revealed dense deposits in the degenerated media of small or medium-sized arteries or the thickened walls of the arterioles. X-ray microanalysis demonstrated the presence of calcium, phosphorus, iron, zinc, magnesium, and aluminum.

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Animals Calcinosis Female Globus Pallidus Macaca fascicularis Male Microscopy, Electron Monkey Diseases Journal Article

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T Yanai, T Masegi, K Ueda, J Manabe, M Teranishi, M Takaoka, N Matsunuma, K Fukuda, N Goto, K Fujiwara. 1994. Vascular mineralization in the monkey brain.. https://doi.org/10.1177/030098589403100506

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