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A probabilistic model for detecting coding regions in DNA sequences.

A Thomas·M H Skolnick
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Abstract

A probabilistic model is presented to predict whether or not an anonymous sequence of DNA contains exons. The method is shown to be at least as reliable as Grail, a well-known neural network solution to the problem, and to be significantly more amenable to customization for specific prediction problems.

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Base SequenceCodonDNAExonsGenetic CodeModels, StatisticalMolecular Sequence DataProbabilityRandom AllocationSoftwareJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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A Thomas, M H Skolnick. 1994. A probabilistic model for detecting coding regions in DNA sequences.. https://doi.org/10.1093/imammb%2F11.3.149

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