Urinary biomarkers and nephrotoxicity.

G A Porter

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PubMed · 7845320

Urinary biomarkers and nephrotoxicity.

G A Porter

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Abstract

Biomarkers represent measurable changes in biologic systems or samples which correlate with an organism's altered biochemical or cellular function. For the kidney urine is the usual body fluid sampled. The principle processes which are evaluated are filtration/elimination and reabsorption/secretion. Proteins, either abnormal in type or amount, and enzymes have dominated interest in this field for many years. However, application of monoclonal antibody techniques, along with an understanding of the role of cytokiness, growth factors, collagen matrix and lipid mediators have rapidly expanded the field of new candidates for urinary biomarkers.

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Biomarkers Humans Kidney Diseases Proteinuria Reproducibility of Results Sensitivity and Specificity Journal Article Review

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G A Porter. 1994. Urinary biomarkers and nephrotoxicity.. https://pubmed.ncbi.nlm.nih.gov/7845320/

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