Auditory middle latency responses under different task conditions.

Abstract

We examined the relationship between the Na and Pa components of human MLRs and the performance of different tasks. We also investigated whether MLRs are reliable indices of activity in the central motor-sensory system. The click stimuli we used consistently evoked the Na and Pa components. At CZ, the Na and Pa components significantly decreased for all tasks other than pegging with right hand while at FZ, these components were significantly decreased for all tasks. The Na and Pa latencies were slightly increased during task performances. These results indicate that the Na and Pa components of human MLRs decreased when various tasks were performed, while subjects were concentrating. A general principle of evoked potentials is that latencies decrease as amplitudes increase in excitation due to neural activation. Thus, it would appear that, under the conditions of this study, the pathways from the reticular formation and the thalamus to the primary auditory cortex were inhibited. Since the thalamus is considered to be the relay region for poly-sensory inputs, it is thought that the attenuation of the MLRs and SEPs occurs at the level of cerebral cortex, including the reticular formation, the thalamus, and the primary auditory cortex. Accordingly, since it is inferred that central factors are responsible for the attenuation of the MLRs, Na and Pa components observed during the performance of tasks carried out in the present experiment, it may be concluded that MLRs are reliable indices of activity in the central-motor system.