[Transrectal echography in tuberculous prostatitis].

E Sánchez Sánchez; I Fernández González; J L Ruiz Rubio; A Herrero Payo; I Romero Cajigal; A Aramburu Gonzalez; J Antonio Moreno; A Berenguer Sánchez

PubMed · 7864669

[Transrectal echography in tuberculous prostatitis].

E Sánchez Sánchez·I Fernández González·J L Ruiz Rubio·A Herrero Payo·I Romero Cajigal·A Aramburu Gonzalez·J Antonio Moreno·A Berenguer Sánchez

View original source ↗Export metadata ↓

Abstract

Tuberculous prostatitis is diagnosed incidentally, when the pathologist is studying a specimen of transurethral resection of the prostate or a prostatic biopsy. There is scant literature on the role of transrectal ultrasound in the diagnosis of this pathology. A case of tuberculous prostatitis is presented, with special reference to the transrectal ultrasound pattern. A complete review of the references on the imaging techniques in this pathology is done.

Explore related subjects

Antitubercular Agents Humans Male Middle Aged Mycobacterium tuberculosis Prostate Prostatitis Tuberculosis, Male Genital Ultrasonography Case Reports Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

E Sánchez Sánchez, I Fernández González, J L Ruiz Rubio, A Herrero Payo, I Romero Cajigal, A Aramburu Gonzalez, J Antonio Moreno, A Berenguer Sánchez. 1994. [Transrectal echography in tuberculous prostatitis].. https://pubmed.ncbi.nlm.nih.gov/7864669/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1998

Tuberculosis one century after R. Koch.

The molecular revolution is beginning to have an impact on all aspects of tuberculosis. Work in diagnostics is expected to progress in maximizing genetic testing of mycobacteria. Drug development will benefit from recently acquired knowledge on molecular mechanisms of drug action. The availability of the complete genome of Mycobacterium tuberculosis, and better tools for genetic work with mycobacteria, will promote the development of vaccine candidates. Our work has contributed to the definition of the mechanisms of resistance to rifampin, fluoroquinolones, and ethambutol, and, using molecular analysis, to a better understanding of the epidemiology of mycobacterial infections. This overview of the direction of tuberculosis research today illustrates the impact of novel scientific approaches on the investigation of old problems.

Antitubercular Agents↗

PubMed1998

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis.

The preferred antitubercular drug isoniazid specifically targets a long-chain enoyl-acyl carrier protein reductase (InhA), an enzyme essential for mycolic acid biosynthesis in Mycobacterium tuberculosis. Despite the widespread use of this drug for more than 40 years, its precise mode of action has remained obscure. Data from x-ray crystallography and mass spectrometry reveal that the mechanism of isoniazid action against InhA is covalent attachment of the activated form of the drug to the nicotinamide ring of nicotinamide adenine dinucleotide bound within the active site of InhA.

Antitubercular Agents↗

PubMed1998

The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy.

The principal side effect of the antimycobacterial agent ethambutol (EMB) is an optic neuropathy with clinical features very similar to a mitochondrial hereditary optic neuropathy (Leber's). The mechanism of EMB-induced optic neuropathy may be EMB's chelation of copper, thereby precluding normal cytochrome c oxidase activity and mitochondrial metabolism in the optic nerve. Before attempting to use therapeutic copper to replenish endogenous stores in an attempt to preclude EMB-induced optic neuropathy, we wished to determine whether EMB is still effective against mycobacteria in the presence of copper. EMB and copper, alone and in combination, were tested against six strains of Mycobacterium tuberculosis and five strains of Mycobacterium avium using a radiometric broth macrodilution assay. Copper did not effect EMB's antimicrobial actions against either species of mycobacteria. This in vitro study suggests that if copper were given to patients to prevent EMB-induced optic neuropathy, it would not compromise EMB's bacteriostatic properties.

Antitubercular Agents↗