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PubMed · 7872556

[Diprivan: intubation without curare].

G D'Honneur
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Abstract

To intubate under ideal conditions, i.e. with the vocal cords abducted and no motor response to the insertion of the endotracheal tube, the anaesthetist has two alternatives: to use muscle relaxants or to anaesthetize the patient deeply. Apart from cases where muscle relaxants are contra-indicated or required by the type of procedure: Intubation using muscle relaxants means: maintaining the option of varying the depth of anaesthesia, while keeping optimal conditions for intubation; reducing the risk of airways trauma. Intubation without muscle relaxants means: avoiding the risk of allergic complications; producing deep anaesthesia and controlling any resulting haemodynamic effects. The recommended induction agent is propofol, given as a bolus injection at a dose equal to or greater than 2.5 mg.kg-1 in adults and 3.5 mg.kg-1 in children. Alfentanil is the opioid of choice, the dose being between 30 and 40 micrograms.kg-1. Lidocaine, injected as premedication at a dose of 1.5 mg.kg-1 potentiates the effect of alfentanil. The order of injection of the induction agents is important, as it determines the exact moment for laryngoscopy and intubation.

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Anesthesia, IntravenousCurareHumansIntubation, IntratrachealNeuromuscular Blocking AgentsPropofolEnglish AbstractJournal Article

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G D'Honneur. 1994. [Diprivan: intubation without curare].. https://doi.org/10.1016/s0750-7658(05)80708-7

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